Extra material

We have a separate page with extra non-public reading material available at www.tcblab.org/outgoing/proteinphysics. You can e-mail Magnus Andersson to get the password if you are registered on the course, or ask during class.

• Lecture 1:
  Introduction, proteins, amino acids. Chapters 1 & 2 of the book. slides-2016
  The review by David Eisenberg - it's a good read - and will facilitate your understanding of protein secondary structure - optional though. 2003_Review

• Lecture 2: 
  Molecular interactions (chapters 3-4).  slides-2016
  Cyrus Levinthals paper in Scientific American on protein structure & folding - good introduction - but optional for this course. Levinthal

• Lecture 3: 
  Thermodynamics, defining hydrophobic effect from free energies, electrostatics (chapter 5-6). slides-2016

• Lecture 4: 
  Secondary structure (chapters 7,10). Note that we cover chapters 8 & 9 later! slides-2016

• Lecture 5: 
  Statistical mechanics, the partition function, phase transitions & a-helix formation (chapter 8 & 9 (to p. 109)). slides-2016

• Lecture 6: 
  Protein secondary structure formation and free energy (rest of chapter 9). slides-2016

• Lecture 7: 
  Fibrous proteins and globular proteins with alpha-helix and beta-sheet structure (chapter 11, 13 & 14). slides-2016

• Lecture 8: 
  Membranes & membrane proteins (chapter 12, but we will deviate a lot from the book)

• Lecture 9: 
  Protein folds (chapter 15-16). slides-2016

• Lecture 10:
  Denaturation & the character of transitions - cooperativity or not (chapter 17-18). slides-2016

• Lecture 11:
  Kinetics of protein folding (chapters 19-21). slides-2016

• Lecture 12:
  Prediction and design of protein structure, bioinformatics (chapters 22-23). slides-2016

• Lecture 13:
  GPCRs, docking and drug design (chapters 24-25, deviate a lot from the book). slides-2016

• Lecture 14:
  Course repetition. slides