Extra material

We have a separate page with extra non-public reading material available at www.tcblab.org/outgoing/proteinphysics. You can e-mail Magnus Andersson to get the password if you are registered on the course, or ask during class.

• Lecture 1: Tuesday Jan 20, 3-5pm, Room FA31
  Introduction, proteins, amino acids. Chapters 1 & 2 of the book. slides
  The review by David Eisenberg - it's a good read - and will facilitate your understanding of protein secondary structure - optional though. 2003_Review

• Lecture 2: Tuesday Jan 22, 1-3pm, Room FE21
  Molecular interactions (chapters 3-4).  slides
  Cyrus Levinthals paper in Scientific American on protein structure & folding - good introduction - but optional for this course. Levinthal

• Lecture 3: Monday Jan 27, 3-5pm, Room FE21
  Thermodynamics, defining hydrophobic effect from free energies, electrostatics (chapter 5-6). slides

• Lecture 4: Thursday Jan 29, 1-3pm, Room FA31
  Secondary structure (chapters 7,10). Note that we cover chapters 8 & 9 later! slides

• Lecture 5: Monday Feb 3, 10-12am, Room FA31
  Statistical mechanics, the partition function, phase transitions & a-helix formation (chapter 8 & 9 (to p. 109)). slides

• Lecture 6: Thursday February 6, 10-12am, Room FA31
  Protein secondary structure formation and free energy (rest of chapter 9). slides

• Lecture 7: Friday February 13, 8-10am, Room FE21
  Fibrous proteins and globular proteins with alpha-helix and beta-sheet structure (chapter 11, 13 & 14). slides

• Lecture 8: Thursday February 19, 1-3pm, Room FD41 
  Membranes & membrane proteins (chapter 12, but we will deviate a lot from the book). slides

• Lecture 9: Friday February 20, 10-12am, Room FB54
  Protein folds (chapter 15-16). slides

• Lecture 10:Tuesday February 24, 10-12am, Room FA31
  Denaturation & the character of transitions - cooperativity or not (chapter 17-18). slides

• Lecture 11:Thursday Feb 26, 1-3pm, Room FA31
  Kinetics of protein foldning (chapters 19-21). slides

• Lecture 12:Friday Feb 27, 1-3pm, Room FE21
  Prediction and design of protein structure, bioinformatics (chapters 22-23). slides

• Lecture 13:Tuesday March 3, 10-12am, Room FA31
  GPCRs, docking and drug design (chapters 24-25, deviate a lot from the book). slides

• Lecture 14:Friday March 5, 3-5pm, Room FA31
  Course repetition. slides