A new study shows that in colon cancer hedgehog signalling has a protective function

A new study from the Karolinska Institutet, published in the journal Nature Communications, for the first time demonstrates that in colon cancer hedgehog signalling has a protective function.

ki.se/en/news/active-hedgehog-signalling-in-connective-tissue-cells-protects-against-colon-cancer

Publication

Stromal hedgehog signalling is downregulated in colon cancer and its restoration restrains tumour growth
Marco Gerling, Nikè V.J.A. Büller, Leonard M. Kirn, Simon Joost, Oliver Frings, Benjamin Englert, Åsa Bergström, Raoul V. Kuiper, Leander Blaas, Mattheus C.B. Wielenga, Sven Almer, Anja A. Kühl, Erik Fredlund, Gijs R. van den Brink and Rune Toftgård.
Nature Communications, published online 5 Augusti 2016, doi 10.1038/NCOMMS12321