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Publications by Per Berglund

Peer reviewed

Articles

[1]
Heinks, T., Merz, L. M., Liedtke, J., Hoehne, M., van Langen, L. M., Bornscheuer, U. T. ... Berglund, P. (2023). Biosynthesis of Furfurylamines in Batch and Continuous Flow by Immobilized Amine Transaminases. Catalysts, 13(5), 875.
[2]
Sheludko, Y. V., Slagman, S., Gittings, S., Charnock, S. J., Land, H., Berglund, P. & Fessner, W. (2022). Enantioselective Synthesis of Pharmaceutically Relevant Bulky Arylbutylamines Using Engineered Transaminases. Advanced Synthesis and Catalysis, 364(17), 2972-2981.
[3]
Högfeldt, A.-K., Gumaelius, L., Berglund, P., Kari, L., Pears, A. & Kann, V. (2022). Leadership, support and organisation for academics'€™ participation in engineering education change for sustainable development. European Journal of Engineering Education.
[4]
Kretschmer, M., Ceña-Diez, R., Butnarasu, C., Silveira, V., Dobryden, I., Visentin, S. ... Yan, H. (2022). Synthetic Mucin Gels with Self-Healing Properties Augment Lubricity and Inhibit HIV-1 and HSV-2 Transmission. Advanced Science, 9(32), 2203898.
[5]
Merz, L. M., van Langen, L. M. & Berglund, P. (2022). The Role of Buffer, Pyridoxal 5'-phosphate and Light on the Stability of the Silicibacter Pomeroyi Transaminase. ChemCatChem, n/a(n/a).
[6]
Fiorati, A., Berglund, P., Svedendahl, M. & Tessaro, D. (2020). Application of Transaminases in a Disperse System for the Bioamination of Hydrophobic Substrates. Advanced Synthesis and Catalysis, 362(5), 1156-1166.
[7]
Marx, L., Ríos‐Lombardía, N., Süss, P., Höhne, M., Morís, F., González‐Sabín, J. & Berglund, P. (2020). Chemoenzymatic Synthesis of Sertraline. European Journal of Organic Chemistry, 2020(4), 510-513.
[8]
Land, H., Ruggieri, F., Szekrenyi, A., Fessner, W.-D. & Berglund, P. (2020). Engineering the Active Site of an (S)-Selective Amine Transaminase for Acceptance of Doubly Bulky Primary Amines. Advanced Synthesis and Catalysis, 362(4), 812-821.
[9]
Land, H., Campillo-Brocal, J. C., Svedendahl Humble, M. & Berglund, P. (2019). B-factor Guided Proline Substitutions in Chromobacterium violaceum Amine Transaminase – An Evaluation of the Proline Rule as a Method for Enzyme Stabilization. ChemBioChem (Print), 20(10), 1297-1304.
[10]
Ruggieri, F., Campillo-Brocal, J. C., Chen, S., Humble, M. S., Walse, B., Logan, D. D. T. & Berglund, P. (2019). Insight into the dimer dissociation process of the Chromobacterium violaceum (S)-selective amine transaminase. Scientific Reports, 9.
[11]
Chen, S., Campillo-Brocal, J. C., Berglund, P. & Svedendahl Humble, M. (2018). Characterization of the stability of Vibrio fluvialis JS17 amine transaminase. Journal of Biotechnology, 282, 10-17.
[12]
Marx, L., Rios-Lombardia, N., Farnberger, J. F., Kroutil, W., Benitez-Mateos, A. I., Lopez-Gallego, F. ... Berglund, P. (2018). Chemoenzymatic Approaches to the Synthesis of the Calcimimetic Agent Cinacalcet Employing Transaminases and Ketoreductases. Advanced Synthesis and Catalysis, 360(11), 2157-2165.
[13]
Abahazi, E., Satorhelyi, P., Erdelyi, B., Vertessy, B. G., Land, H., Paizs, C. ... Poppe, L. (2018). Covalently immobilized Trp60Cys mutant of omega‰-transaminase from Chromobacterium violaceum for kinetic resolution of racemic amines in batch and continuous-flow modes. Biochemical engineering journal, 132, 270-278.
[14]
Chen, S., Berglund, P. & Svedendahl Humble, M. (2018). The effect of phosphate group binding cup coordination on the stability of the amine transaminase from Chromobacterium violaceum. Molecular Catalysis, 446, 115-123.
[15]
Ruggieri, F., van Langen, L. M., Logan, D. T., Walse, B. & Berglund, P. (2018). Transaminase-catalyzed racemization with potential for dynamic kinetic resolutions. ChemCatChem, 10(21), 5026-5032.
[16]
Guo, F. & Berglund, P. (2017). Transaminase biocatalysis : optimization and application. Green Chemistry, 19(2), 333-360.
[17]
Steffen-Munsberg, F., Matzel, P., Sowa, M. A., Berglund, P., Bornscheuer, U. T. & Höhne, M. (2016). Bacillus anthracis ω-amino acid:pyruvate transaminase employs a different mechanism for dual substrate recognition than other amine transaminases. Applied Microbiology and Biotechnology, 100, 4511-4521.
[18]
Palo-Nieto, C., Afewerki, S., Anderson, M., Tai, C.-W., Berglund, P. & Córdova, A. (2016). Integrated Heterogeneous Metal/Enzymatic Multiple Relay Catalysis for Eco-Friendly and Asymmetric Synthesis. ACS Catalysis, 6, 3932-3940.
[19]
Land, H., Hendil-Forssell, P., Martinelle, M. & Berglund, P. (2016). One-pot biocatalytic amine transaminase/acyl transferase cascade for aqueous formation of amides from aldehydes or ketones. catalysis science & technology, 6, 2897-2900.
[20]
Chen, S., Land, H., Berglund, P. & Svedendahl Humble, M. (2016). Stabilization of an amine transaminase for biocatalysis. Journal of Molecular Catalysis B : Enzymatic, 124, 20-28.
[21]
Steffen-Munsberg, F., Vickers, C., Kohls, H., Land, H., Mallin, H., Nobili, A. ... Bornscheuer, U. T. (2015). Bioinformatic analysis of a PLP-dependent enzyme superfamily suitable for biocatalytic applications. Biotechnology Advances, 33(5), 566-604.
[22]
Scheidt, T., Land, H., Anderson, M., Chen, Y., Berglund, P., Yi, D. & Fessner, W.-D. (2015). Fluorescence-Based Kinetic Assay for High-Throughput Discovery and Engineering of Stereoselective omega-Transaminases. Advanced Synthesis and Catalysis, 357(8), 1721-1731.
[23]
Kohls, H., Anderson, M., Dickerhoff, J., Weisz, K., Cordova, A., Berglund, P. ... Hoehne, M. (2015). Selective Access to All Four Diastereomers of a 1,3-Amino Alcohol by Combination of a Keto Reductase- and an Amine Transaminase-Catalysed Reaction. Advanced Synthesis and Catalysis, 357(8), 1808-1814.
[24]
Gaffney, D., Abdallah, N. H., Cooney, J. C., Laffir, F. R., Engelmark Cassimjee, K., Berglund, P. ... Magner, E. (2014). Preparation and characterisation of a Ni2+/Co2+-cyclam modified mesoporous cellular foam for the specific immobilisation of His(6)-alanine racemase. Journal of Molecular Catalysis B : Enzymatic, 109, 154-160.
[25]
Anderson, M., Afewerki, S., Berglund, P. & Cõrdova, A. (2014). Total Synthesis of Capsaicin Analogues from Lignin-Derived Compounds by Combined Heterogeneous Metal, Organocatalytic and Enzymatic Cascades in One Pot. Advanced Synthesis and Catalysis, 356(9), 2113-2118.
[26]
Wang, B., Land, H. & Berglund, P. (2013). An efficient single-enzymatic cascade for asymmetric synthesis of chiral amines catalyzed by omega-transaminase. Chemical Communications, 49(2), 161-163.
[27]
Steffen-Munsberg, F., Vickers, C., Thontowi, A., Schätzle, S., Tumlirsch, T., Svedendahl Humble, M. ... Höhne, M. (2013). Connecting Unexplored Protein Crystal Structures to Enzymatic Function. ChemCatChem, 5(1), 150-153.
[28]
Steffen-Munsberg, F., Vickers, C., Thontowi, A., Schätzle, S., Meinhardt, T., Svedendahl Humble, M. ... Höhne, M. (2013). Revealing the Structural Basis of Promiscuous Amine Transaminase Activity. ChemCatChem, 5(1), 154-157.
[29]
Cassimjee, K. E., Humble, M. S., Land, H., Abedi, V. & Berglund, P. (2012). Chromobacterium violaceum omega-transaminase variant Trp60Cys shows increased specificity for (S)-1-phenylethylamine and 4 '-substituted acetophenones, and follows Swain-Lupton parameterisation. Organic and biomolecular chemistry, 10(28), 5466-5470.
[30]
Svedendahl Humble, M., Engelmark Cassimjee, K., Håkansson, M., Kimbung, Y. R., Walse, B., Abedi, V. ... Logan, D. T. (2012). Crystal structures of the Chromobacterium violaceumω-transaminase reveal major structural rearrangements upon binding of coenzyme PLP. The FEBS Journal, 279(5), 779-792.
[31]
Svedendahl Humble, M., Engelmark Cassimjee, K., Abedu, V., Federsel, H.-J. & Berglund, P. (2012). Key Amino Acid Residues for Reversed or Improved Enantiospecificity of an omega-Transaminase. ChemCatChem, 4(8), 1167-1172.
[32]
Engelmark Cassimjee, K., Marí­n, S. R. & Berglund, P. (2012). Synthesis of cyclic polyamines by enzymatic generation of an amino aldehyde in situ. Macromolecular rapid communications, 33(18), 1580-1583.
[33]
Cassimjee, K. E., Humble, M. S., Miceli, V., Colomina, C. G. & Berglund, P. (2011). Active Site Quantification of an omega-Transaminase by Performing a Half Transamination Reaction. ACS Catalysis, 1(9), 1051-1055.
[34]
Svedendahl Humble, M. & Berglund, P. (2011). Biocatalytic Promiscuity. European Journal of Organic Chemistry(19), 3391-3401.
[35]
Cassimjee, K. E., Kourist, R., Lindberg, D., Larsen, M. W., Thanh, N. H., Widersten, M. ... Berglund, P. (2011). One-step enzyme extraction and immobilization for biocatalysis applications. Biotechnology Journal, 6(4), 463-469.
[36]
Vongvilai, P., Linder, M., Sakulsombat, M., Humble, M. S., Berglund, P., Brinck, T. & Ramström, O. (2011). Racemase Activity of B. cepacia Lipase Leads to Dual-Function Asymmetric Dynamic Kinetic Resolution of alpha-Aminonitriles. Angewandte Chemie International Edition, 50(29), 6592-6595.
[37]
Svedendahl, M., Branneby, C., Lindberg, L. & Berglund, P. (2010). Reversed Enantiopreference of an omega-Transaminase by a Single-Point Mutation. CHEMCATCHEM, 2(8), 976-980.
[38]
Engelmark Cassimjee, K., Branneby, C., Abedi, V., Wells, A. & Berglund, P. (2010). Transaminations with isopropyl amine : equilibrium displacement with yeast alcohol dehydrogenase coupled to in situ cofactor regeneration. Chemical Communications, 46(30), 5569-5571.
[39]
Svedendahl, M., Jovanovic, B., Fransson, L. & Berglund, P. (2009). Suppressed Native Hydrolytic Activity of a Lipase to Reveal Promiscuous Michael Addition Activity in Water. CHEMCATCHEM, 1(2), 252-258.
[40]
Svedendahl, M., Carlqvist, P., Branneby, C., Allnér, O., Frise, A., Hult, K. ... Brinck, T. (2008). Direct Epoxidation in Candida antarctica Lipase B Studied by Experiment and Theory. ChemBioChem (Print), 9(15), 2443-2451.
[41]
Cassimjee, K. E., Trummer, M., Branneby, C. & Berglund, P. (2008). Silica-immobilized His(6)-tagged enzyme : Alanine racemase in hydrophobic solvent. Biotechnology and Bioengineering, 99(3), 712-716.
[42]
Hult, K. & Berglund, P. (2007). Enzyme promiscuity : mechanism and applications. Trends in Biotechnology, 25(5), 231-238.
[43]
Carlqvist, P., Svedendahl, M., Branneby, C., Hult, K., Brinck, T. & Berglund, P. (2005). Exploring the Active-Site of a Rationally Redesigned Lipase for Catalysis of Michael-Type Additions. ChemBioChem (Print), 6, 331-336.
[44]
Svedendahl, M., Hult, K. & Berglund, P. (2005). Fast carbon-carbon bond formation by a promiscuous lipase. Journal of the American Chemical Society, 127(51), 17988-17989.
[46]
Berglund, P. & Park, S. (2005). Strategies for altering enzyme reaction specificity for applied biocatalysis. Current organic chemistry, 9(4), 325-336.
[47]
Branneby, C., Carlqvist, P., Hult, K., Brinck, T. & Berglund, P. (2004). Aldol Additions with Mutant Lipase : Analysis by Experiments and Theoretical Calculations. Journal of Molecular Catalysis B : Enzymatic, 31(4-6), 123-128.
[48]
Berglund, P., Branneby, C., Svedendahl Humble, M., Carlqvist, P., Magnusson, A., Hult, K. & Brinck, T. (2003). Aldol and Michael additions catalyzed by a rationally redesigned hydrolytic enzyme. Abstracts of Papers of the American Chemical Society, 226(2), U155-U156.
[49]
Branneby, C., Carlqvist, P., Magnusson, A., Hult, K., Brinck, T. & Berglund, P. (2003). Carbon-Carbon Bonds by Hydrolytic Enzymes. Journal of the American Chemical Society, 125(4), 874-875.
[50]
Hult, K. & Berglund, P. (2003). Engineered enzymes for improved organic synthesis. Current Opinion in Biotechnology, 14(4), 395-400.
[51]
Branneby, C., Carlqvist, P., Hult, K., Brinck, T. & Berglund, P. (2003). Rational redesign of a lipase to an aldolase. Biochemistry, 42(28), 8633-8633.
[52]
Hedin, Eva. M. K., Patkar, S. A., Vind, J., Svendsen, A., Hult, K. & Berglund, P. (2002). Selective reduction and chemical modification of oxidized lipase cysteine mutants. Canadian journal of chemistry (Print), 80(6), 529-539.
[53]
Berglund, P. (2001). Controlling lipase enantioselectivity for organic synthesis. Biomolecular Engineering, 18(1), 13-22.
[54]
Berglund, P., Christiernin, M. & Hedenström, E. (2001). Enantiorecognition of chiral acids by Candida rugosa lipase : Two substrate binding modes evidenced in an organic medium. American Chemical Society Symposium Series (ACS), 776, 263-273.
[55]
Berglund, P., Hedenstrom, E. & Hult, K. (2000). Controlling lipase enantioselectivity for organic synthesis. Abstracts of Papers of the American Chemical Society, 219(1), U219-U219.
[56]
Holmquist, M. & Berglund, P. (2000). Improved lipase enantioselectivity by combinatorial and rational redesign. Abstracts of Papers of the American Chemical Society, 219(1), U163-U163.
[58]
Berglund, P., Vallikivi, I., Fransson, L., Dannacher, H., Holmquist, M., Martinelle, M. ... Hult, K. (1999). Switched enantiopreference of Humicola lipase for 2-phenoxyalkanoic acid ester homologs can be rationalized by different substrate binding modes. Tetrahedron : asymmetry, 10(21), 4191-4202.
[59]
Berglund, P., Holmquist, M. T. & Hult, K. (1998). Reversed enantiopreference of Candida rugosa lipase supports different modes of binding enantiomers of a chiral acyl donor. Journal of Molecular Catalysis - B Enzymatic, 5(1-4), 283-287.
[60]
DeSantis, G., Berglund, P., Stabile, M. R., Gold, M. & Jones, J. B. (1998). Site-directed mutagenesis combined with chemical modification as a strategy for altering the specificity of the S1 and S1' pockets of subtilisin Bacillus lentus. Biochemistry, 37(17), 5968-5973.
[61]
Berglund, P., DeSantis, G., Stabile, M. R., Shang, X., Gold, M., Bott, R. R. ... Jones, J. B. (1997). Chemical Modification of Cysteine Mutants of Subtilisin Bacillus lentus Can Create Better Catalysts Than the Wild-Type Enzyme. Journal of the American Chemical Society, 119(22), 5265-5266.
[62]
Bydén, M., Edlund, H., Berglund, P. & Lindström, B. (1997). Phase equilibria in two aqueous chiral surfactant systems. Progress in Colloid and Polymer Science, 105, 360-364.
[63]
Berglund, P., Stabile, M. R., Gold, M., Jones, J. B., Mitchinson, C., Bott, R. R. & Graycar, T. P. (1996). Altering the specificity of subtilisin B. lentus by combining site-directed mutagenesis and chemical modification. Bioorganic & Medicinal Chemistry Letters, 6(21), 2507-2512.
[64]
Edlund, H., Berglund, P., Jensen, M., Hedenström, E. & Högberg, H. -. (1996). Resolution of 2-methylalkanoic acids. Enantioselective esterification with long chain alcohols catalysed by Candida rugosa lipase. Acta Chemica Scandinavica, 50(8), 666-671.
[65]
Berglund, P., Holmquist, M., Hult, K. & Hogberg, H. -. (1995). Alcohols as enantioselective inhibitors in a lipase catalysed esterification of a chiral acyl donor. Biotechnology Letters, 17(1), 55-60.
[66]
Högberg, H. -., Berglund, P., Edlund, H., Fägerhag, J., Hedenström, E., Lundh, M. ... Vörde, C. (1994). Biocatalysis as a useful tool in pheromone synthesis. Enantiomerically pure building blocks from baker's yeast reductions and enzyme catalysed resoluti. Catalysis Today, 22(3), 591-606.
[67]
[68]
Berglund, P., Holmquist, M. T., Hedenstrom, E., Hult, K. & Hogberg, H.-E. (1993). 2-Methylalkanoic acids resolved by esterification catalysed by lipase from Candida rugosa : Alcohol chain length and enantioselectivity. Tetrahedron Asymmetry, 4(8), 1869-1878.
[69]
Holmquist, M. T., Martinelle, M., Berglund, P., Clausen, I. G., Patkar, S., Svendsen, A. & Hult, K. (1993). Lipases from Rhizomucor miehei and Humicola lanuginosa : Modification of the lid covering the active site alters enantioselectivity. Journal of Protein Chemistry, 12(6), 749-757.
[70]
Högberg, H.-E., Edlund, H., Berglund, P. & Hedenström, E. (1993). WATER ACTIVITY INFLUENCES ENANTIOSELECTIVITY IN A LIPASE-CATALYZED RESOLUTION BY ESTERIFICATION IN AN ORGANIC-SOLVENT. Tetrahedron : asymmetry, 4(10), 2123-2126.
[71]
Holmberg, E., Holmquist, M. T., Hedenstrom, E., Berglund, P., Norin, T., Hogberg, H.-E. & Hult, K. (1991). Reaction conditions for the resolution of 2-methylalkanoic acids in esterification and hydrolysis with lipase from Candida cylindracea. Applied Microbiology and Biotechnology, 35(5), 572-578.

Conference papers

[72]
Högfeldt, A.-K., Kann, V., Berglund, P., Kari, L., Gumaelius, L., Pears, A. (2021). Organizing for Capacity and Involvement among Faculty, Students and Staff in Engineering Education Change : 10 Years of Development. In Proceedings of 2021 World Engineering Education Forum/Global Engineering Deans Council, WEEF/GEDC 2021. (pp. 340-348). Institute of Electrical and Electronics Engineers Inc.
[73]
Högfeldt, A.-K., Kann, V., Berglund, P., Gumaelius, L., Pears, A. (2020). Mellan vision och praktik i förändring : Övergripande arenor och nätverk som hållbara mötesplatser?. In Hållbart lärande..
[74]
Högfeldt, A.-K., Andersson, M., Berglund, P., Bergman, M., Delin, A., Edström, K., Geschwind, L., Grillner, K., Håkansson, A., Kari, L., Karlsson, S., Lilliesköld, J., Nilsson, M., Pears, A. (2019). Pedagogisk meritering på KTH - Samarbete, excellens och utbildningsinnovation. In Bidrag från 7:e Utvecklingskonferensen för Sveriges ingenjörsutbildningar. (pp. 76-81). Luleå: Luleå University of Technology.
[75]
Karlsson, S., Berglund, P. (2012). Education Assessment Exercise (EAE) - A path to quality enhancement in engineering education?. In Proceedings of the 40th SEFI Annual Conference 2012 - Engineering Education 2020: Meet the Future. European Society for Engineering Education (SEFI).

Chapters in books

[76]
Berglund, P., Svedendahl Humble, M. & Branneby, C. (2012). 7.18 C-X Bond Formation : Transaminases as Chiral Catalysts: Mechanism, Engineering, and Applications. In Comprehensive Chirality (pp. 390-401). Elsevier.
[77]
Berglund, P. (2005). Enzymes Engineered for New Reactions - Novel Catalysts for Organic Synthesis. In Pandey, A.; Webb, C.; Soccol, C. R.; Larroche, C. (Ed.), Enzyme Technology (pp. 175-188). New Delhi: AsiaTech Publishers.
[78]
Berglund, P. & Hedenström, E. (2001). Preparation of 2-, 3-, and 4-methylcarboxylic acids and the corresponding alcohols of high enantiopurity by lipase-catalyzed esterification. In Vulfson, E. N.; Halling, P. J.; Holland, H. L. (Ed.), Enzymes in Nonaqueous Solvents: Methods and Protocols (pp. 307-317). Totowa: Humana Press.
[79]
Berglund, P. & Hult, K. (2000). Biocatalytic synthesis of enantiopure compounds using lipases : Chapter 21. In Patel, R. N. (Ed.), Stereoselective Biocatalysis (pp. 633-657). New York: Marcel Dekker.

Non-peer reviewed

Articles

[80]
Svedendahl, M., Engelmark Cassimjee, K., Branneby, C., Abedi, V., Wells, A. & Berglund, P. (2010). CASCAT : Redesign of omega-Transaminases for Synthesis of Chiral Amines. Journal of Biotechnology, 150, S123-S124.
[81]
Berglund, P. (2008). Asymmetric Organic Synthesis with Enzymes : Edited by Vicente Gotor, Ignacio Alfonso and Eduardo Garcia-Urdiales. Angewandte Chemie International Edition, 47(35), 6514-6515.

Conference papers

[83]
Karlsson, S., Berglund, P., Malmström, E. (2011). Ledarskap i kravfylld tid : utveckling genom utvärdering vid KTH. Presented at SUHF:s ledarskapskonferens: Att leda högre utbildning, KI, Solna, 14-15 nov 2011.
[84]
Berglund, P., Högfeldt, A.-K., Karlsson, S., Klasén, I., Sandberg, T. (2011). Utvärdering för utveckling : KTH:s samtliga utbildningar under belysning. Presented at 3:e utvecklingskonferensen för Sveriges ingenjörsutbildningar, session 2B:Kvalitetsarbete, Norrköping, SE.

Chapters in books

[85]
Berglund, P., Dannetun, P., Chan, W. L., Gold, J., Han, S., Hansson, H. ... Ellervik, U. (2019). Linking Education and Research : A Roadmap for Higher Education Institutions at the Dawn of the Knowledge Society. In Linking education and research: the results of an international Summer School (pp. 11-33). Basel: MDPI.

Theses

[86]
Berglund, P. (1995). Candida rugosa lipase as a catalyst in organic media : Enantioselectivity in kinetic resolutions of 2-methylalkanoic acids (Doctoral thesis , KTH Royal Institute of Technology, Stockholm, Trita-IOK 26). Retrieved from http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-83735.

Patents

Patents

[87]
Córdova, A., Berglund, P., Anderson, M. & Afewerki, S. (2015). Efficient Synthesis Of Amines And Amides From Alcohols And Aldehydes By Using Cascade Catalysis. WO2015144902-A1.
[88]
Hauer, B., Engelmark Cassimjee, D. K. & Berglund, P. (2009). Process for producing polyamines. WO 2011051433.
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