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This advanced course provides training on the methods used for microbial community analysis including recent innovations in metagenomics, metatranscriptomics, metaproteomics, and functional metagenomics. Students will investigate a series of case studies of meta-omics analysis of environmental and human-associated microbial communities.
Recent years have seen an explosion of large datasets generated on microbial communities in natural and industrial environments, thanks to advances in metagenomics and related technologies. These new data can give insight into human health and disease, or the fitness of a natural environment. In addition, these data can inform biotechnological interventions into the microbiota for improved digestion or food production, or can be a source of new industrially relevant enzymes.
The course will cover five key themes:
T1. Introduction to advanced microbiology, and metagenomic methodology.
T2. Metagenomics for enzyme discovery in biotechnology.
T3. The human microbiome – roles in health and disease.
T4. Current and emerging methods for microbial diagnostics in the clinical setting.
T5. The environmental microbiome – function and metagenomic monitoring approaches.