Sophia Hober is Professor of Molecular Biotechnology at KTH, Stockholm, Sweden. She is part of the executive management team of the Human Protein Atlas and the Secretome project. Also, from 2011 to 2015 she was dean of faculty at KTH and thereby also part of the executive management team at KTH. She has published more than 115 scientific papers.
The focus of her current research group is development of predictable and robust systems for protein purification and detection through protein design and various selection methodologies. Her key scientific achievements include characterization of the folding pathway of IGF‑1, design and development of gene fusion systems for selective ion‑exchange purification. Further more, she has developed a novel protein domain with calcium dependent affinity and improved the alkaline tolerance of protein A and protein G for industrial purification of IgG/HSA (currently a product sold by GE Healthcare). Moreover, small bispecific protein domains with ability to strongly and selectively bind to two different proteins have been developed. These domains have been designed for use in protein purification as well as for cancer theranostics.
For more detailed information about the research of the group, please visit The Hober Lab
2001 Docent, Dept. of Biotech. KTH, Stockholm
1996 PhD, Biochemistry, Dept. of Biotechnology, KTH, Stockholm.
1988 M.Sc., (Civ.Ing.) Chemical Engineering/Biotechnology, KTH, Stockholm, Sweden
2007 – Professor of Molecular Biotechnology, KTH, Stockholm, Sweden
2011 –2015 Dean of Faculty (80%), KTH, Stockholm, Sweden
2007 – 2009 Vice Dean, School of Biotechnology, KTH, Stockholm, Sweden
2003 – 2009 Site‑director HPA, KTH, Stockholm, Sweden
2005 – 2006 Associate Prof. (Universitetslektor), School of Biotechnology, KTH, Stockholm, Sweden
1997 – 2000 Assistant Prof. (Forskarassistent), Dept. of Biotechnology, KTH, Stockholm, Sweden
1996 – 2005 Senior Scientist, Dept. of Biochemistry and Biotechnology, KTH, Stockholm, Sweden
1989 – 1996 Doctoral Fellowship, Dept. of Biochemistry and Biotechnology, KTH, but located at Pharmacia, Stockholm, Sweden
Industriell rening av biologiska produkter (CB2010), examinator, kursansvarig | Kurswebb