Postdoc (scholarship) in Computational Biophysics
KTH Royal Institute of Technology in Stockholm has grown to become one of Europe’s leading technical and engineering universities, as well as a key centre of intellectual talent and innovation. We are Sweden’s largest technical research and learning institution and home to students, researchers and faculty from around the world. Our research and education covers a wide area including natural sciences and all branches of engineering, as well as architecture, industrial management, urban planning, history and philosophy
KTH Engineering Sciences carries out a wide range of research at the international front line, from fundamental disciplines such as Physics and Mathematics, to Engineering Mechanics with applications such as Aeronautics and Vehicle Engineering. We also offer university degree programs in Engineering Physics, Vehicle Engineering, and 'Open entrance', as well as a number of international master’s programs.
Project description
The department of applied physics is looking for a new postdoctoral scholar in computational biophysics, in particular for studying ion channel function using computational tools.
Membrane proteins, such as ion channels, enable cells to communicate with the outside world and are important pharmacological targets. The study of their function can be hampered by limitations in the experimental setups, making computer simulations a complementary tool of choice to investigate the details of their mechanics.
However, ion channel gating and allosteric regulation involves conformational changes occurring over time scales that are typically longer than the ones that can be directly observed using MD simulations. The project thus involves developing protocols that allow to sample these conformational changes using enhanced sampling techniques, by taking advantage of what is already known about the process (via interpretation of experimental results and/or long time-scale simulations). In a second step, the simulation output will be analyzed and interpreted.
The collaboration in the group is highly international and cross-disciplinary. You will be a member of a research team with high-paced work, and the project includes collaborations with our international partner groups in the US.
Qualifications
The successful candidate is expected to have a PhD in physics, chemistry, biochemistry or biotechnology. Experience with simulations of membrane proteins, enhanced sampling techniques and/or interfacing with experiments on membrane proteins will be an advantage.
Applicants must be strongly motivated to learn and develop new skills, possess the ability to work independently and perform critical analysis. Applicants will also have a demonstrated ability to collaborate in teams and to communicate research in a written and oral form. Note that a good command of English is essential, both as the local group language and because of our international collaborations.
Application
Apply to this scholarship by e-mail to scholarshipapplication@sci.kth.se You are the main responsible to ensure that your application is complete according to the ad. Your complete application must be received at KTH no later than 2018-07-06. Mark your application with reference number S-2018-0910.
The application must include the following documents:
- Curriculum vitae
- Cover letter (detailing both your previous scientific work experience and your interest in this position)
- Contact information for three references
Please observe that you apply for a scholarship, not an employment.
Other information
Period: 1 year starting as soon as possible, with a possibility to extend for an additional year.
Extent: Full-time
Amount of scholarship: 25 000 kr/month
Location: SciLifeLab Stockholm
Contact
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