Aména Jocelyne Archer

Senior scientist and Lab manager

I am a senior scientist and lab manager in the Williams Lab (Experimental Oncology).

·      Research activity: sex differences, estrogen signaling, cancer, metabolism, genome-wide gene regulation

·      Supervision and teaching

Ethics resource

I am also working as ethics advisor to provide information and guidance to KTH’s researchers on ethical applications for research activities involving humans and animals.

If you have any question about ethical applications, you are welcome to contact me directly:

Selected publications

Intestinal estrogen receptor beta modulates the murine colon tumor immune microenvironment. Birgersson M, Holm M, Gallardo-Dodd CJ, Chen B, Stepanauskaitė L, Hases L, Kutter C, Archer A, Williams C. Cancer Lett. (2025) PMID: 40120798.

Spatial profiling of the mouse colonic immune landscape associated with colitis and sex. Holm M, Stepanauskaitė L, Bäckström A, Birgersson M, Socciarelli F, Archer A, Stadler C, Williams C. Commun Biol. (2024) doi: 10.1038/s42003-024-07276-1.

Estrogen receptor activation remodels TEAD1 gene expression to alleviate hepatic steatosis. Sommerauer C, Gallardo-Dodd CJ, Savva C, Hases L, Birgersson M, Indukuri R, Shen JX, Carravilla P, Geng K, Nørskov Søndergaard J, Ferrer-Aumatell C, Mercier G, Sezgin E, Korach-André M, Petersson C, Hagström H, Lauschke VM, Archer A, Williams C, Kutter C.  Mol Syst Biol. (2024) doi: 10.1038/s44320-024-00024-x.

High-fat diet and estrogen modulate the gut microbiota in a sex-dependent manner in mice. Hases L, Stepanauskaite L, Birgersson M, Brusselaers N, Schuppe-Koistinen I, Archer A, Engstrand L, Williams C. Commun Biol. (2023) doi: 10.1038/s42003-022-04406-5.

Ovarian ERβ cistrome and transcriptome reveal chromatin interaction with LRH-1. Birgersson M, Indukuri R, Lindquist L, Stepanauskaite L, Luo Q, Deng Q, Archer A, Williams C. BMC Biol. (2023) doi: 10.1186/s12915-023-01773-1.

Colitis Induces Sex-Specific Intestinal Transcriptomic Responses in Mice. Hases L, Birgersson M, Indukuri R, Archer A, Williams C. Int J Mol Sci. (2022) PMID: 36142324.

Genome-wide estrogen receptor β chromatin binding in human colon cancer cells reveals its tumor suppressor activity.Indukuri R, Jafferali MH, Song D, Damdimopoulos A, Hases L, Zhao C, Archer A, Williams C. Int J Cancer (2021) PMID: 33754337.

Blocking Fra-1 sensitizes triple-negative breast cancer to PARP inhibitor. Song D, He H, Sinha I, Hases L, Yan F, Archer A, Haldosen LA, Zhao C, Williams C. Cancer Lett (2021) PMID: 33652085.

Intestinal estrogen receptor beta suppresses colon inflammation and tumorigenesis in both sexes. Hases L, Indukuri R, Birgersson M, Nguyen-Vu T, Lozano R, Saxena A, Hartman J, Frasor J, Gustafsson JÅ, Katajisto P, Archer A, Williams C. Cancer Lett(2020) PMID: 32711097.