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Publications by Björn Önfelt

Peer reviewed

Articles

[1]
Q. Hammer et al., "Genetic ablation of adhesion ligands mitigates rejection of allogeneic cellular immunotherapies," Cell Stem Cell, vol. 31, no. 9, pp. 1376-1386.e8, 2024.
[4]
V. Carannante, M. Wiklund and B. Önfelt, "In vitro models to study natural killer cell dynamics in the tumor microenvironment," Frontiers in Immunology, vol. 14, 2023.
[5]
P. Sandoz et al., "Modulation of lytic molecules restrain serial killing in γδ T lymphocytes," Nature Communications, vol. 14, no. 1, 2023.
[7]
A. H. M. Tay et al., "A(2B) adenosine receptor antagonists rescue lymphocyte activity in adenosine-producing patient-derived cancer models," Journal for ImmunoTherapy of Cancer, vol. 10, no. 5, pp. e004592, 2022.
[9]
N. Sandström et al., "Live single cell imaging assays in glass microwells produced by laser-induced deep etching," Lab on a Chip, vol. 22, no. 11, pp. 2107-2121, 2022.
[11]
K. Tuomela et al., "Radiotherapy transiently reduces the sensitivity of cancer cells to lymphocyte cytotoxicity," Proceedings of the National Academy of Sciences of the United States of America, vol. 119, no. 3, pp. e2111900119, 2022.
[12]
[17]
K. Olofsson et al., "Ultrasound-Based Scaffold-Free Core-Shell Multicellular Tumor Spheroid Formation," Micromachines, vol. 12, no. 3, 2021.
[18]
S. J. Edwards et al., "High-Resolution Imaging of Tumor Spheroids and Organoids Enabled by Expansion Microscopy," Frontiers in Molecular Biosciences, vol. 7, 2020.
[19]
J. Dunst et al., "Recognition of synthetic polyanionic ligands underlies “spontaneous” reactivity of Vγ1 γδTCRs," Journal of Leukocyte Biology, vol. 107, no. 6, pp. 1033-1044, 2020.
[20]
C. L. Fleming et al., "A Fluorescent Kinase Inhibitor that Exhibits Diagnostic Changes in Emission upon Binding," Angewandte Chemie International Edition, 2019.
[21]
P. E. Olofsson et al., "A collagen-based microwell migration assay to study NK-target cell interactions," Scientific Reports, vol. 9, 2019.
[23]
I. Prager et al., "NK cells switch from granzyme B to death receptor–mediated cytotoxicity during serial killing," Journal of Experimental Medicine, vol. 7, no. 9, pp. 2113-2127, 2019.
[25]
D. Sarha et al., "161533 TriKE stimulates NK-cell function to overcome myeloid-derived suppressor cells in MDS," Blood Advances, vol. 2, no. 12, pp. 1459-1469, 2018.
[26]
K. Olofsson et al., "Acoustic formation of multicellular tumor spheroids enabling on-chip functional and structural imaging," Lab on a Chip, vol. 18, no. 16, pp. 2466-2476, 2018.
[27]
M. Kördel et al., "Biological Laboratory X-ray Microscopy," Microscopy and Microanalysis, vol. 24, no. S2, pp. 346-347, 2018.
[28]
K. Walwyn-Brown et al., "Human NK Cells Lyse Th2-Polarizing Dendritic Cells via NKp30 and DNAM-1," Journal of Immunology, vol. 201, no. 7, pp. 2028-2041, 2018.
[29]
V. Y. S. Oei et al., "Intrinsic Functional Potential of NK-Cell Subsets Constrains Retargeting Driven by Chimeric Antigen Receptors," CANCER IMMUNOLOGY RESEARCH, vol. 6, no. 4, pp. 467-480, 2018.
[30]
A. Stikvoort et al., "Risk Factors for Severe Acute Graft-versus-Host Disease in Donor Graft Composition," Biology of blood and marrow transplantation, vol. 24, no. 3, pp. 467-477, 2018.
[31]
K. Srpan et al., "Shedding of CD16 disassembles the NK cell immune synapse and boosts serial engagement of target cells," Journal of Cell Biology, vol. 217, no. 9, pp. 3267-3283, 2018.
[32]
E. Fogelqvist et al., "Laboratory cryo x-ray microscopy for 3D cell imaging," Scientific Reports, vol. 7, 2017.
[33]
K. Guldevall et al., "Microchip screening Platform for single cell assessment of NK cell cytotoxicity," Frontiers in Immunology, vol. 7, 2016.
[34]
H.-T. Hsu et al., "NK cells converge lytic granules to promote cytotoxicity and prevent bystander killing," Journal of Cell Biology, vol. 215, no. 6, pp. 875-889, 2016.
[35]
M. Enqvist et al., "Coordinated expression of DNAM-1 and LFA-1 in educated NK cells," Journal of Immunology, vol. 194, no. 9, pp. 4518-4527, 2015.
[37]
J. P. Goodridge, B. Onfelt and K.-J. Malmberg, "Newtonian cell interactions shape natural killer cell education," Immunological Reviews, vol. 267, no. 1, pp. 197-213, 2015.
[40]
P. E. Olofsson et al., "Distinct Migration and Contact Dynamics of Resting and IL-2-Activated Human Natural Killer Cells.," Frontiers in immunology, vol. 5, pp. 80, 2014.
[41]
M. Wiklund et al., "Ultrasound-Induced Cell-Cell Interaction Studies in a Multi-Well Microplate," Micromachines, vol. 5, no. 1, pp. 27-49, 2014.
[42]
B. Vanherberghen et al., "Classification of human natural killer cells based on migration behavior and cytotoxic response," Blood, vol. 121, no. 8, pp. 1326-1334, 2013.
[43]
I. Parmryd and B. Önfelt, "Consequences of membrane topography," The FEBS Journal, vol. 280, no. 12, pp. 2775-2784, 2013.
[44]
M. Ohlin et al., "Influence of acoustic streaming on ultrasonic particle manipulation in a 100-well ring-transducer microplate," Journal of Micromechanics and Microengineering, vol. 23, no. 3, pp. 035008, 2013.
[45]
[46]
M. Sternberg-Simon et al., "Natural killer cell inhibitory receptor expression in humans and mice : A closer look," Frontiers in Immunology, vol. 4, no. March, pp. 65, 2013.
[47]
M. Wiklund, H. Brismar and B. Önfelt, "Acoustofluidics 18 : Microscopy for acoustofluidic micro-devices," Lab on a Chip, vol. 12, no. 18, pp. 3221-3234, 2012.
[50]
K. Wilkinson et al., "Visualization of custom-tailored iron oxide nanoparticles chemistry, uptake, and toxicity," Nanoscale, vol. 4, no. 23, pp. 7383-7393, 2012.
[51]
T. Frisk et al., "A silicon-glass microwell platform for high-resolution imaging and high-content screening with single cell resolution," Biomedical microdevices (Print), vol. 13, no. 4, pp. 683-693, 2011.
[52]
M. A. Khorshidi et al., "Analysis of transient migration behavior of natural killer cells imaged in situ and in vitro," Integrative Biology, vol. 3, no. 7, pp. 770-778, 2011.
[53]
J. R. Nilsson et al., "Light-induced cytotoxicity of a photochromic spiropyran," Chemical Communications, vol. 47, no. 39, pp. 11020-11022, 2011.
[54]
K. Guldevall et al., "Imaging Immune Surveillance of Individual Natural Killer Cells Confined in Microwell Arrays," PLOS ONE, vol. 5, no. 11, pp. e15453, 2010.
[55]
J. Hurtig, D. T. Chiu and B. Önfelt, "Intercellular nanotubes : insights from imaging studies and beyond," WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY, vol. 2, no. 3, pp. 260-276, 2010.
[56]
B. Vanherberghen et al., "Ultrasound-controlled cell aggregation in a multi-well chip," Lab on a Chip, vol. 10, no. 20, pp. 2727-2732, 2010.
[57]
O. Manneberg et al., "Flow-free transport of cells in microchannels by frequency-modulated ultrasound," Lab on a Chip, vol. 9, pp. 833-837, 2009.
[59]
O. Manneberg et al., "A three-dimensional ultrasonic cage for characterization of individual cells," Applied Physics Letters, vol. 93, pp. 063901, 2008.
[60]
R. K. P. Benninger et al., "Fluorescence-lifetime imaging of DNA-dye interactions within continuous-flow microfluidic systems," Angewandte Chemie International Edition, vol. 46, no. 13, pp. 2228-2231, 2007.
[63]
[64]
C. Dunsby et al., "An electronically tunable ultrafast laser source applied to fluorescence imaging and fluorescence lifetime imaging microscopy," Journal of Physics D : Applied Physics, vol. 37, no. 23, pp. 3296-3303, 2004.
[65]
B. Önfelt and D. M. Davis, "Can membrane nanotubes facilitate communication between immune cells?," Biochemical Society Transactions, vol. 32, pp. 676-678, 2004.
[66]
K. Eleme et al., "Cell surface organization of stress-inducible proteins ULBP and MICA that stimulate human NK cells and T cells via NKG2D," Journal of Experimental Medicine, vol. 199, no. 7, pp. 1005-1010, 2004.
[67]
S. B. Taner et al., "Control of immune responses by trafficking cell surface proteins, vesicles and lipid rafts to and from the immunological synapse," Traffic : the International Journal of Intracellular Transport, vol. 5, no. 9, pp. 651-661, 2004.
[68]
B. Önfelt et al., "Cutting edge : Membrane nanotubes connect immune cells," Journal of Immunology, vol. 173, no. 3, pp. 1511-1513, 2004.
[69]
J. Olofsson, B. Önfelt and P. Lincoln, "Three-state light switch of Ru(phen)(2)dppz (2+) : Distinct excited-state species with two, one, or no hydrogen bonds from solvent," Journal of Physical Chemistry A, vol. 108, no. 20, pp. 4391-4398, 2004.
[70]
B. Önfelt et al., "Picosecond and steady-state emission of Ru(phen)(2)dppz (2+) in glycerol : Anomalous temperature dependence," Journal of Physical Chemistry A, vol. 107, no. 7, pp. 1000-1009, 2003.
[72]
J. Olofsson et al., "Picosecond Kerr-gated time-resolved resonance Raman spectroscopy of the Ru(phen)(2)dppz (2+) interaction with DNA," Journal of Inorganic Biochemistry, vol. 91, no. 1, pp. 286-297, 2002.
[73]
B. Önfelt, P. Lincoln and B. Norden, "Enantioselective DNA threading dynamics by phenazine-linked Ru(phen)(2)dppz (2+) dimers," Journal of the American Chemical Society, vol. 123, no. 16, pp. 3630-3637, 2001.
[74]
C. G. Coates et al., "Picosecond time-resolved resonance Raman probing of the light-switch states of Ru(Phen)(2)dppz (2+)," Journal of Physical Chemistry B, vol. 105, no. 50, pp. 12653-12664, 2001.
[75]
B. Önfelt et al., "Femtosecond linear dichroism of DNA-intercalating chromophores : Solvation and charge separation dynamics of Ru(phen)(2)dppz (2+) systems," Proceedings of the National Academy of Sciences of the United States of America, vol. 97, no. 11, pp. 5708-5713, 2000.
[76]
E. Tuite et al., "Probing DNA conductivity with photoinduced electron transfer and scanning tunneling microscopy," Journal of Biomolecular Structure and Dynamics, pp. 277-283, 2000.

Conference papers

[77]
N. Sandström et al., "Laser-induced deep etching of glass for live cell assays," in MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, 2021, pp. 579-580.
[78]
K. Olofsson et al., "Single cell resolution analysis of ultrasound-produced multi-cellular tumor spheroids," in 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017, 2020, pp. 955-956.
[79]
M. Kördel et al., "Biological Laboratory X-Ray Microscopy," in X-Ray Nanoimaging : Instruments and Methods IV, 2019.
[80]
K. Olofsson et al., "High-content nucleus based 3D image cytometery of whole multicellular tumour spheroids," in 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018, 2018, pp. 1433-1434.
[81]
K. Olofsson et al., "Unanchored micro-tumors in an ultrasonic actuated multi-well microplate with protein repellent coating," in 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016, 2016, pp. 409-410.
[82]
A. Christakou et al., "Characterization of natural killer cell immune surveillance against solid liver tumors," in MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, 2015, pp. 915-917.
[83]
A. E. Christakou et al., "Solid tumor spheroid formation by temperature-controlled high voltage ultrasound in a multi-well microdevice," in 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014, 2014, pp. 573-575.
[84]
M. Wiklund et al., "On-chip acoustic sample preparation for cell studies and diagnostics," in Proceedings of Meetings on Acoustics : Volume 19, 2013, 2013, pp. 1-3.
[85]
M. Ohlin et al., "Analysis of trapping and streaming in an ultrasoundactuated multi-well microplate for single-cell studies," in Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012, 2012, pp. 497-499.
[86]
A. E. Christakou et al., "Characterization of natural killer cells' cytotoxic heterogeneity using an array of sono-cages," in Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012, 2012, pp. 1555-1557.
[87]
Athanasia. E. Christakou et al., "Aggregation and long-term positioning of cells by ultrasound in a multi-well microchip for high-resolution imaging of the natural killer cell immune synapse," in 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011, 2011, pp. 329-331.
[88]
M. Ohlin et al., "Controlling acoustic streaming in a multi-well microplate for improving live cell assays," in 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011, 2011, pp. 1612-1614.
[89]
B. Önfelt, "NATURAL KILLER CELL IMMUNE SURVEILLANCE AT THE SINGLE CELL LEVEL," in PROGRESS ON POST-GENOME TECHNOLOGIES AND MODERN NATURAL PRODUCTS, 2011, 2011, pp. 55-55.
[90]
K. Guldevall et al., "Imaging immune surveillance by individual Natural Killer cells isolated in arrays of nanoliter wells," in 12th Meeting of the Society for Natural Immunity, NK2010. Cavtat-Dubrovnik, Croatia. April 20-24, 2010, 2010.
[91]
T. Frisk et al., "Live-cell imaging of natural killer cell mediated tumor rejection in arrays of microwells," in 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010 : Volume 2, 2010, pp. 950-952.
[92]
O. Manneberg et al., "Ultrasonic microcages for high-resolution characterization of individual cells," in 12th Annual European Conference on Micro & Nanoscale Technologies for the Biosciences, NanoTech 2008. Montreux, Switzerland. November 17-19 2008, 2008.

Non-peer reviewed

Articles

[93]
T. Kienzle et al., "Characterization of interactions between monocytes and mesenchymal stromal cells," Cytotherapy, vol. 25, no. 6, pp. S63-S63, 2023.
[95]
Q. Hammer et al., "Genetic ablation of adhesion ligands effectively averts rejection of allogeneic immune cells," European Journal of Immunology, vol. 52, pp. 23-23, 2022.
[98]
[100]
L. Brandt et al., "Cytotoxicity and killing kinetics of KIR educated NK cells," Scandinavian Journal of Immunology, vol. 86, no. 4, pp. 301-301, 2017.
[101]
Q. Verron et al., "Microchip screening for single cell assessment and isolation of serial killing NK cells," Scandinavian Journal of Immunology, vol. 86, no. 4, pp. 347-347, 2017.
[102]
V. Carannante et al., "Novel platform for studying infiltration, migration and cytotoxicity of human Natural Killer cells in solid tumors," Scandinavian Journal of Immunology, vol. 86, no. 4, pp. 315-315, 2017.
[103]
S. Meinke et al., "Platelets become NK cell targets in the presence of anti-platelet antibodies," Scandinavian Journal of Immunology, vol. 86, no. 4, pp. 257-258, 2017.
[106]
M. A. Khorshidi, B. Vanherberghen and B. Önfelt, "Natural Killer Cell-Mediated Tumor Surveillance : Correlation Between Killing Efficiency, Transient Migration Behavior and Morphology," Biophysical Journal, vol. 102, no. 3, pp. 706A-706A, 2012.

Conference papers

[107]
B. Vanherberghen et al., "Highly parallelized cell aggregation by ultrasound for studies of immune cell interaction," in 7th USWNet Meeting: Unidirectional motion produced by vibrating fields for cell/particle and fluid control. Stockholm, Sweden. Nov. 30th - Dec. 1st, 2009, 2009.

Chapters in books

[108]
V. Carannante et al., "Generation of tumor spheroids in microwells to study NK cell cytotoxicity, infiltration and phenotype," in Methods in Cell Biology, : Elsevier BV, 2023, pp. 195-208.
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