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Publications by Per-Olof Syrén

Peer reviewed

Articles

[1]
S. Subramaniyan et al., "Designing from biobased to closed-loop circularity: Flexible dynamic polyimine-amide networks," Chemical Engineering Journal, vol. 501, 2024.
[2]
B. A. Nebel et al., "A Career in Catalysis : Bernhard Hauer," ACS Catalysis, vol. 13, no. 13, pp. 8861-8889, 2023.
[3]
D. A. Hueting et al., "Design, structure and plasma binding of ancestral β-CoV scaffold antigens," Nature Communications, vol. 14, no. 1, 2023.
[4]
S. Subramaniyan et al., "Designed for Circularity : Chemically Recyclable and Enzymatically Degradable Biorenewable Schiff Base Polyester-Imines," ACS Sustainable Chemistry and Engineering, vol. 11, no. 8, pp. 3451-3465, 2023.
[6]
[9]
B. Guo et al., "Conformational Selection in Biocatalytic Plastic Degradation by PETase," ACS Catalysis, vol. 12, no. 6, pp. 3397-3409, 2022.
[10]
D. A. Hueting, S. R. Vanga and P.-O. Syrén, "Thermoadaptation in an Ancestral Diterpene Cyclase by Altered Loop Stability," Journal of Physical Chemistry B, vol. 126, no. 21, pp. 3809-3821, 2022.
[13]
C. Jönsson et al., "Biocatalysis in the Recycling Landscape for Synthetic Polymers and Plastics towards Circular Textiles," ChemSusChem, vol. 14, no. 19, pp. 4028-4040, 2021.
[14]
K. Schriever et al., "Engineering of Ancestors as a Tool to Elucidate Structure, Mechanism, and Specificity of Extant Terpene Cyclase," Journal of the American Chemical Society, vol. 143, no. 10, pp. 3794-3807, 2021.
[16]
A. Stamm et al., "Pinene-Based Oxidative Synthetic Toolbox for Scalable Polyester Synthesis," JACS Au, vol. 1, no. 11, pp. 1949-1960, 2021.
[19]
W. Farhat et al., "Lactone monomers obtained by enzyme catalysis and their use in reversible thermoresponsive networks," Journal of Applied Polymer Science, vol. 137, no. 18, 2020.
[20]
A. Stamm et al., "A retrobiosynthesis-based route to generate pinene-derived polyesters," ChemBioChem, vol. 20, pp. 1664-1671, 2019.
[21]
W. Farhat et al., "Biocatalysis for terpene-based polymers," Zeitschrift für Naturforschung C - A Journal of Biosciences, vol. 74, no. 3-4, pp. 90-99, 2019.
[22]
A. Stamm et al., "Chemo- enzymatic pathways toward pinene- based renewable materials," Green Chemistry, vol. 21, no. 10, pp. 2720-2731, 2019.
[23]
A. Biundo et al., "Switched reaction specificity in polyesterases towards amide bond hydrolysis by enzyme engineering," RSC Advances, vol. 9, no. 62, pp. 36217-36226, 2019.
[24]
N. Hendrikse et al., "Ancestral diterpene cyclases show increased thermostability and substrate acceptance," The FEBS Journal, vol. 285, no. 24, pp. 4660-4673, 2018.
[25]
P.-O. Syrén, "Enzymatic Hydrolysis of Tertiary Amide Bonds by anti Nucleophilic Attack and Protonation," Journal of Organic Chemistry, vol. 83, no. 21, pp. 13543-13548, 2018.
[27]
A. Eriksson, C. Kürten and P.-O. Syrén, "Protonation-Initiated Cyclization by a ClassII Terpene Cyclase Assisted by Tunneling," ChemBioChem, vol. 18, no. 23, pp. 2301-2305, 2017.
[28]
N. M. Hendrikse et al., "Redesign of biosynthetic enzymes using ancestral sequence reconstruction," The FEBS Journal, vol. 284, pp. 86-87, 2017.
[29]
M. J. Fink and P.-O. Syrén, "Redesign of water networks for efficient biocatalysis," Current opinion in chemical biology, vol. 37, pp. 107-114, 2017.
[30]
J. Fagerland et al., "Template-assisted enzymatic synthesis of oligopeptides from a polylactide chain," Biomacromolecules, vol. 18, no. 12, pp. 4271-4280, 2017.
[31]
C. Kürten, B. Carlberg and P.-O. Syren, "Mechanism-Guided Discovery of an Esterase Scaffold with Promiscuous Amidase Activity," Catalysts, vol. 6, no. 6, 2016.
[32]
P.-O. Syrén et al., "Squalene-hopene cyclases : evolution, dynamics and catalytic scope," Current opinion in structural biology, vol. 41, pp. 73-82, 2016.
[33]
[34]
C. Kürten and P.-O. Syren, "Unraveling Entropic Rate Acceleration Induced by Solvent Dynamics in Membrane Enzymes," Journal of Visualized Experiments, no. 107, 2016.
[35]
P. Hendil-Forssell, M. Martinelle and P.-O. Syren, "Exploring water as building bricks in enzyme engineering," Chemical Communications, vol. 51, no. 97, pp. 17221-17224, 2015.
[36]
C. Kürten, M. Uhlén and P.-O. Syrén, "Overexpression of functional human oxidosqualene cyclase in Escherichia coli," Protein Expression and Purification, vol. 115, pp. 46-53, 2015.
[37]
P.-O. Syrén et al., "Entropy is Key to the Formation of Pentacyclic Terpenoids by Enzyme-Catalyzed Polycyclization," Angewandte Chemie International Edition, vol. 53, no. 19, pp. 4845-4849, 2014.
[38]
P.-O. Syrén et al., "Proton Shuttle Mechanism in the Transition State of Lipase-Catalyzed N-Acylation of Amino Alcohols," ChemCatChem, vol. 5, no. 7, pp. 1842-1853, 2013.
[39]
S. C. Hammer et al., "Squalene hopene cyclases : highly promiscuous and evolvable catalysts for stereoselective CC and CX bond formation," Current opinion in chemical biology, vol. 17, no. 2, pp. 293-300, 2013.
[40]
M. Seitz et al., "Synthesis of Heterocyclic Terpenoids by Promiscuous Squalene-Hopene Cyclases," ChemBioChem, vol. 14, no. Copyright (C) 2013 American Chemical Society (ACS). All Rights Reserved., pp. 436-439, 2013.
[41]
P.-O. Syren, "The solution of nitrogen inversion in amidases," The FEBS Journal, vol. 280, no. 13, pp. 3069-3083, 2013.
[43]
S. C. Hammer et al., "Stereoselective Friedel-Crafts alkylation catalyzed by squalene hopene cyclases," Tetrahedron, vol. 68, no. Copyright (C) 2013 American Chemical Society (ACS). All Rights Reserved., pp. 7624-7629, 2012.
[44]
P.-O. Syrén and K. Hult, "Amidases have a hydrogen bond that facilitates nitrogen inversion but esterases have not," ChemCatChem, vol. 3, no. 5, pp. 853-860, 2011.
[45]
K. Engström et al., "Mutated variant of Candida antarctica lipase B in (S)-selective dynamic kinetic resolution of secondary alcohols," Organic and biomolecular chemistry, vol. 9, no. 1, pp. 81-82, 2011.
[46]
P.-O. Syren et al., "Increased activity of enzymatic transacylation of acrylates through rational design of lipases," Journal of Molecular Catalysis B : Enzymatic, vol. 65, no. 1-4, pp. 3-10, 2010.
[47]
[48]
[49]
P.-O. Syrén and K. Hult, "Substrate Conformations Set the Rate of Enzymatic Acrylation by Lipases," ChemBioChem, vol. 11, no. 6, pp. 802-810, 2010.

Chapters in books

[51]
I. V. Pavlidis, N. Hendrikse and P.-O. Syrén, "Computational Techniques for Efficient Biocatalysis," in Modern Biocatalysis : Advances Towards Synthetic Biological Systems, Gavin Williams, Mélanie Hall Ed., : Royal Society of Chemistry, 2018, pp. 119-152.
[52]
P.-O. Syrén, "Understanding esterase and amidase reaction specificities by molecular modelling," in Understanding enzymes; Function, Design, Engineering and Analysis, : Pan Standford Publishing, 2016, p. 523.

Non-peer reviewed

Articles

[54]
W. Farhat et al., "Enzymatic route for the synthesis of norcamphor lactone and its polymerization for applications as thermo-sensitive networks," Abstracts of Papers of the American Chemical Society, vol. 258, 2019.
[55]
L. Fogelström et al., "New chemo-enzymatic pathways for sustainable terpene-based polymeric materials," Abstracts of Papers of the American Chemical Society, vol. 257, 2019.
[56]
E. Malmström et al., "Sustainable terpene-based polymeric materials," Abstracts of Papers of the American Chemical Society, vol. 257, 2019.
[57]
A. Biundo et al., "Increasing amide acceptance on a polyester-hydrolyzing enzyme," New Biotechnology, vol. 33, pp. S105-S105, 2016.
[58]
P.-O. Syrén and K. Hult, "Least-motion mechanism in enzyme catalysis," The FEBS Journal, vol. 277, pp. 263-263, 2010.

Chapters in books

[59]
P.-O. Syrén, "Understanding esterase and amidase reaction specificities by molecular modeling," in Understanding Enzymes: Function, Design, Engineering and Analysis, : Pan Stanford Publishing, 2016, pp. 523-558.

Theses

[60]
P.-O. Syrén, "On electrostatic effects, minimal motion and other catalytic strategies used by enzymes," Doctoral thesis Stockholm : KTH Royal Institute of Technology, Trita-BIO-Report, 14, 2011.

Other

[63]
X. Lopez-Lorenzo, R. Ganapathy and P.-O. Syrén, "Conformational Selection in Enzyme-Catalyzed Depolymerization of Bio-based Polyesters," (Manuscript).
Latest sync with DiVA:
2024-12-08 02:03:42