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Publications

50 latest publications

[1]
De Oliveira, D. H., Gowda, V., Sparrman, T., Gustafsson, L., Pires, R. S., Riekel, C. ... Hedhammar, M. (2024). Structural conversion of the spidroin C-terminal domain during assembly of spider silk fibers. Nature Communications, 15(1).
[2]
Dannemeyer, M., Berling, A., Kanje, S., Enstedt, H., Xu, L., Afshari, D. ... Tegel, H. (2024). Fast and robust recombinant protein production utilizing episomal stable pools in WAVE bioreactors. Protein Expression and Purification, 221.
[3]
Aniander, G. (2024). Improved candidate screening through tailored co-culture assays and precise tuning of protein expression (Licentiate thesis , KTH Royal Institute of Technology, TRITA-CBH-FOU 2024:17). Retrieved from https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-346648.
[4]
Bragina, O., Tashireva, L., Loos, D., Chernov, V., Hober, S. & Tolmachev, V. (2024). Evaluation of Approaches for the Assessment of HER2 Expression in Breast Cancer by Radionuclide Imaging Using the Scaffold Protein [<sup>99m</sup>Tc]Tc-ADAPT6. Pharmaceutics, 16(4).
[5]
Hao, M.-S., Mazurkewich, S., Li, H., Kvammen, A., Saha, S., Koskela, S. ... McKee, L. S. (2024). Structural and biochemical analysis of family 92 carbohydrate-binding modules uncovers multivalent binding to β-glucans. Nature Communications, 15(1).
[6]
Yan, J., Bangalore, C. R., Nikouyan, N., Appelberg, S., Silva, D. N., Yao, H. ... Saellberg, M. (2024). Distinct roles of vaccine-induced SARS-CoV-2-specific neutralizing antibodies and T cells in protection and disease. Molecular Therapy, 32(2), 540-555.
[7]
Lundmark, F., Vorobyeva, A., Liu, Y., Lindbo, S., Xu, T., Oroujeni, M. ... Garousi, J. (2024). Reduction of renal activity retention of radiolabeled albumin binding domain-derived affinity proteins using a non-residualizing label strategy compared with a cleavable glycine-leucine-glycine-lysine-linker. Molecular Medicine Reports, 29(2).
[8]
Parks, L., Ek, M., Ståhl, S. & Löfblom, J. (2024). Investigation of an AIDA-I based expression system for display of various affinity proteins on Escherichia coli. Biochemical and Biophysical Research Communications - BBRC, 696.
[9]
Pinto, S., Hosseini, M., Buckley, S. T., Yin, W., Garousi, J., Gräslund, T. ... Sarmento, B. (2024). Nanoparticles targeting the intestinal Fc receptor enhance intestinal cellular trafficking of semaglutide. Journal of Controlled Release, 366, 621-636.
[10]
Mebrahtu, A., Aniander, G., Mega, A., Moradi, M., Thalén, N., Gudmundsdotter, L. ... Rockberg, J. (2024). Co-culture platform for tuning of cancer receptor density allows for evaluation of bispecific immune cell engagers. New Biotechnology, 79, 120-126.
[11]
Marking, U., Bladh, O., Aguilera, K., Yang, Y., Greilert Norin, N., Blom, K. ... Thålin, C. (2024). Humoral immune responses to the monovalent xbb.1.5-adapted bnt162b2 mrna booster in sweden. The Lancet - Infectious diseases, 24(2), e80-e81.
[12]
Thalén, N., Moradi, M., Lundqvist, M., Rodhe, J., Andersson, M., Bidkhori, G. ... Rockberg, J. (2024). Tuning of CHO secretional machinery improve activity of secreted therapeutic sulfatase 150-fold. Metabolic engineering, 81, 157-166.
[13]
De Oliveira, D. H., Gowda, V., Sparrman, T., Riekel, C., Barth, A., Lendel, C. & Hedhammar, M. (2023). Structural studies of the C-terminal domain of Major ampullate Spidroin 1 present alpha-helical to coil/beta-sheet transition upon fiber formation. Protein Science, 32(12).
[14]
Nilvebrant, J., Hober, S. & Kanje, S. (2023). Ligand and use thereof. us 11820802 (2023-11-21).
[15]
Mortensen, A. C. L., Berglund, H., Segerström, L., Walle, M., Hofström, C., Persson, H. ... Nestor, M. (2023). Selection, characterization and in vivo evaluation of novel CD44v6-targeting antibodies for targeted molecular radiotherapy. Scientific Reports, 13(1).
[16]
Collodet, C., Blust, K., Gkouma, S., Ståhl, E., Chen, X., Hartman, J. & Hedhammar, M. (2023). Development and characterization of a recombinant silk network for 3D culture of immortalized and fresh tumor-derived breast cancer cells. Bioengineering and Translational Medicine, 8(5).
[17]
De Oliveira, D. H. (2023). Integrative structural biology of protein fibers: Spider silk and beta-lactoglobulin nanofibrils (Doctoral thesis , Kungliga tekniska högskolan, Stockholm, Sweden 2023, TRITA-CBH-FOU 2023:56). Retrieved from https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-339602.
[18]
Möller, M., Jönsson, M., Lundqvist, M., Hedin, B., Larsson, L., Larsson, E. ... Hober, S. (2023). An easy-to-use high-throughput selection system for the discovery of recombinant protein binders from alternative scaffold libraries. Protein Engineering Design & Selection, 36.
[19]
Johansson, C. (2023). Proteomic strategies for blood biomarker development in rare dystrophinopathies (Doctoral thesis , KTH Royal Institute of Technology, Stockholm, Sweden, TRITA-CBH-FOU 2023:49). Retrieved from https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-338366.
[20]
Giang, K. A., Sidhu, S. S. & Nilvebrant, J. (2023). Construction of Synthetic Antibody Phage Display Libraries. Methods in Molecular Biology, 2702, 59-75.
[21]
Giang, K. A., Nygren, P.-Å. & Nilvebrant, J. (2023). Selection of Affibody Affinity Proteins from Phagemid Libraries. Methods in Molecular Biology, 2702, 373-392.
[22]
Giang, K. A., Boxaspen, T., Diao, Y., Nilvebrant, J., Kosugi-Kanaya, M., Kanaya, M. ... Nygren, P.-Å. (2023). Affibody-based hBCMA x CD16 dual engagers for NK cell-mediated killing of multiple myeloma cells. New Biotechnology, 77, 139-148.
[23]
Wegrzyniak, O., Zhang, B., Rokka, J., Rosestedt, M., Mitran, B., Cheung, P. ... Eriksson, O. (2023). Imaging of fibrogenesis in the liver by [18F]TZ-Z0959 : an Affibody molecule targeting platelet derived growth factor receptor β. EJNMMI Radiopharmacy and Chemistry, 8(1).
[24]
Bladh, O., Marking, U., Havervall, S., Norin, N. G., Aguilera, K., Hober, S. ... Thålin, C. (2023). Mucosal immune responses following a fourth SARS-CoV-2 vaccine dose. The Lancet Microbe, 4(7), 488.
[25]
Bragina, O., Chernov, V., Schulga, A., Konovalova, E., Hober, S., Deyev, S. ... Tolmachev, V. (2023). Direct Intra-Patient Comparison of Scaffold Protein-Based Tracers, [99mTc]Tc-ADAPT6 and [99mTc]Tc-(HE)3-G3, for Imaging of HER2-Positive Breast Cancer. Cancers, 15(12).
[26]
Wolf-Watz, M., Jönsson, M., Ul Mushtaq, A. & Hober, S. (2023). Calcium-dependent protein folding in a designed molecular switch. Biophysical Journal, 122(3S1).
[27]
Marking, U., Bladh, O., Havervall, S., Svensson, J., Greilert-Norin, N., Aguilera, K. ... Thålin, C. (2023). 7-month duration of SARS-CoV-2 mucosal immunoglobulin-A responses and protection. The Lancet - Infectious diseases, 23(2), 150-152.
[28]
Mega, A., Mebrahtu, A., Aniander, G., Ryer, E., Skold, A., Sandegren, A. ... Frejd, F. Y. (2023). A PDGFRB- and CD40-targeting bispecific AffiMab induces stroma-targeted immune cell activation. mAbs, 15(1).
[29]
Hjelm, L. C., Hedhammar, M. & Löfblom, J. (2023). In vitro Blood-Brain barrier model based on recombinant spider silk protein nanomembranes for evaluation of transcytosis capability of biomolecules. Biochemical and Biophysical Research Communications - BBRC, 669, 77-84.
[30]
Abouzayed, A., Borin, J., Lundmark, F., Rybina, A., Hober, S., Zelchan, R. ... Orlova, A. (2023). The GRPR Antagonist [Tc-99m]Tc-maSSS-PEG(2)-RM26 towards Phase I Clinical Trial : Kit Preparation, Characterization and Toxicity. Diagnostics, 13(9), 1611.
[31]
Marking, U., Havervall, S., Norin, N. G., Bladh, O., Christ, W., Gordon, M. ... Thålin, C. (2023). Correlates of protection and viral load trajectories in omicron breakthrough infections in triple vaccinated healthcare workers. Nature Communications, 14(1).
[32]
Schulte, T., Panas, M. D., Han, X., Williams, L., Kedersha, N., Fleck, J. S. ... McInerney, G. M. (2023). Caprin-1 binding to the critical stress granule protein G3BP1 is influenced by pH. Open Biology, 13(5).
[33]
Cena-Diez, R., Narayanan, A., Ray, S., van de Klundert, M., Rodriguez, J. E., Nilvebrant, J. ... Sonnerborg, A. (2023). Naturally occurring dipeptide from elite controllers with dual anti-HIV-1 mechanism. International Journal of Antimicrobial Agents, 61(5), 106792.
[34]
Yin, W., Xu, T., Ding, H., Zhang, J., Bodenko, V., Tretyakova, M. S. ... Vorobyeva, A. (2023). Comparison of HER2-targeted affibody conjugates loaded with auristatin-and maytansine-derived drugs. Journal of Controlled Release, 355, 515-527.
[35]
Leitao, C. D., Mestre Borras, A., Jonsson, A., Malm, M., Kronqvist, N., Fleetwood, F. ... Lindberg, H. (2023). Display of a naïve affibody library on staphylococci for selection of binders by means of flow cytometry sorting. Biochemical and Biophysical Research Communications - BBRC, 655, 75-81.
[36]
Ornithopoulou, E. (2023). Hierarchical Assembly Investigations and Multiscale Characterization of Protein-based Materials : Insights from Whey Protein Nanofibrils and Recombinant Spider Silk Microspheres (Doctoral thesis , KTH Royal Institute of Technology, TRITA-CBH-FOU 2023:26). Retrieved from https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-327026.
[37]
Mebrahtu, A. (2023). Platforms and strategies harnessing signaling pathways of multifactorial diseases by multispecific antibodies (Doctoral thesis , KTH Royal Institute of Technology, Stockholm, TRITA-CBH-FOU 2023:15). Retrieved from https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-326456.
[38]
Gustafsson, L., Kvick, M., Åstrand, C., Ponsteen, N., Dorka, W. N., Hegrová, V. ... van der Wijngaart, W. (2023). Scalable Production of Monodisperse Bioactive Spider Silk Nanowires. Macromolecular Bioscience, 2200450-2200450.
[39]
Preger, C., Notarnicola, A., Hellström, C., Wigren, E., Fernandes-Cerqueira, C., Kvarnstrom, M. ... Jakobsson, P.-J. (2023). Autoantigenic properties of the aminoacyl tRNA synthetase family in idiopathic inflammatory myopathies. Journal of Autoimmunity, 134.
[40]
Jönsson, M., Scheffel, J., Larsson, E., Möller, M., Rossi, G., Lundqvist, M. ... Hober, S. (2022). CaRA – A multi-purpose phage display library for selection of calcium-regulated affinity proteins. New Biotechnology, 72, 159-167.
[41]
Havervall, S., Marking, U., Svensson, J., Greilert-Norin, N., Bacchus, P., Nilsson, P. ... Thålin, C. (2022). Anti-Spike Mucosal IgA Protection against SARS-CoV-2 Omicron Infection. New England Journal of Medicine, 387(14), 1333-1336.
[42]
Appelberg, S., Ahlén, G., Yan, J., Nikouyan, N., Weber, S., Larsson, O. ... Sällberg, M. (2022). A universal SARS-CoV DNA vaccine inducing highly cross-reactive neutralizing antibodies and T cells. EMBO Molecular Medicine, 14(10).
[43]
Asplund Högelin, K., Ruffin, N., Pin, E., Hober, S., Nilsson, P., Starvaggi Cucuzza, C. ... Al Nimer, F. (2022). B-cell repopulation dynamics and drug pharmacokinetics impact SARS-CoV-2 vaccine efficacy in anti-CD20-treated multiple sclerosis patients. European Journal of Neurology, 29(11), 3317-3328.
[44]
Giang, K. A., Kanaya, M., Boxaspen, T., Kanaya, M., Krokeide, S. Z., Diao, Y. ... Nygren, P.-Å. (2022). Affibody-Based BCMA x CD16 Dual Engagers for Activation of NK Cells Towards Multiple Myeloma. Blood, 140, 10699-10700.
[45]
Orlova, A., Abouzayed, A., Rinne, S., Lushnikova, N., Usynin, E., Doroshenko, A. ... Rybina, A. (2022). Clinical translation of the GRPR antagonist [Tc-99m]Tc-maSSS-PEG(2)-RM26 for targeting prostate tumors. Nuclear Medicine and Biology, 114, S58-S58.
[46]
Preger, C., Notarnicola, A., Hellström, C., Wigren, E., Lundberg, I. E., Jakobsson, P. J. ... Gräslund, S. (2022). Abundant autoantibody isotypes in idiopathic inflammatory myopathies. Annals of the Rheumatic Diseases, 81(Suppl 1), 242.2-243.
[47]
Blixt, L., Bogdanovic, G., Buggert, M., Gao, Y., Hober, S., Healy, K. ... Österborg, A. (2022). Covid-19 in patients with chronic lymphocytic leukemia : clinical outcome and B- and T-cell immunity during 13 months in consecutive patients. Leukemia, 36(2), 476-481.
[48]
Moradi, M., Lundqvist, M., Harris, C., Malm, M., Volk, A.-L., Thalén, N. ... Rockberg, J. (2022). Autophagy and intracellular product degradation genes identified by systems biology analysis reduce aggregation of bispecific antibody in CHO cells. New Biotechnology, 68, 68-76.
[49]
Scheffel, J. (2022). Calcium-dependent Affinity Domains for the Purification of Antibodies and Antibody Fragments (Doctoral thesis , KTH Royal Institute of Technology, Stockholm, TRITA-CBH-FOU 2022:16). Retrieved from https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-309572.
[50]
Mravinacová, S., Jönsson, M., Christ, W., Klingstrom, J., Yousef, J., Hellström, C. ... Hober, S. (2022). A cell-free high throughput assay for assessment of SARS-CoV-2 neutralizing antibodies. New Biotechnology, 66, 46-52.