Postdoc in Antibody Glycoengineering

Job description

Hober lab is dedicated to advancing predictable and robust systems for protein production, purification, and detection. Our research spans protein engineering for therapeutic development, diagnostics, and bioprocessing, as well as the development of high-throughput and pilot-scale production systems.

We are now seeking a highly motivated Postdoc to drive a project focused on glycoengineering of antibodies. The work will center on protein production in mammalian cells, glycosylation pathway engineering, and optimization of IgA production and purification. This project offers an exciting opportunity to develop next-generation therapeutic antibodies by tailoring glycan structures for improved stability, efficacy, and biological activity. A unique strength is integration with the COMMUNITY biobank at Karolinska Institutet, comprising over 60,000 nasal secretion samples with defined protection correlates. Detailed IgA characterization will inform recombinant IgA design, which will be tested in stem cell-derived nasal and lung organoids, directly linking molecular design to human-relevant respiratory immunity models.

We are looking for a Postdoctoral researcher with a solid background in protein production who is eager to apply glycoengineering strategies to advance the design and function of next-generation therapeutic antibodies.

Qualifications

Requirements

• A doctoral degree or an equivalent foreign degree. This eligibility requirement must be met no later than the time the employment decision is made.
• The research profile, as documented by previous publications, including PhD thesis, is aligned with the job description.
• Ability to work independently towards achieving goals of the project. Capability to work in collaboration both in teams and with other researchers as proven by previous publications and projects.
• Good English language skills as proven by previous oral presentations at conferences and other relevant forums. 
• Good communication skills

Preferred qualifications

• A doctoral degree or an equivalent foreign degree, obtained within the last three years prior to the application deadline.
• Motivation and dedication to research work is a very strong merit.
• Awareness of diversity and equal opportunity issues, with specific focus on gender equality
• Independence 

Great emphasis will be placed on personal skills.

Trade union representatives

Contact information to trade union representatives.

To apply for the position

Log into KTH's recruitment system to apply for this position. You are responsible for ensuring that your application is complete according to the instructions in the ad.

Your complete application must be received at KTH no later than the last day of application, midnight CET/CEST (Central European Time/Central European Summer Time).

About the employment

The position offered is for, at the most, two years.

A position as a postdoctoral fellow is a time-limited qualified appointment focusing mainly on research, intended as a first career step after a dissertation.

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About KTH

KTH Royal Institute of Technology in Stockholm has grown to become one of Europe’s leading technical and engineering universities, as well as a key centre of intellectual talent and innovation. We are Sweden’s largest technical research and learning institution and home to students, researchers and faculty from around the world. Our research and education covers a wide area including natural sciences and all branches of engineering, as well as architecture, industrial management, urban planning, history and philosophy. Read more here