Postdoc in Microphysiological Systems for Tumor Biology

Job description

We are looking for a Postdoctoral fellow with the task of validating and developing  new systems to emulate cancer microenvironments. The fellow will work on multidisciplinary projects collaborating with research groups across KTH, Karolinska Institutet, SciLifeLab, and Karolinska Hospital. The host environment will be the Division of Nanobiotechnology, SciLifeLab, KTH with the group of Professor Anna Herland.

The project aim is to simulate the tumor microenvironment at  two levels of complexity:

• Tumor-stroma interactions to uncover self-reinforcing ligand secretion patterns, which could become the target of novel therapies. This approach will be strongly supported by in silico digital-twin-like models of these interactions.
• Vascularization of tumor models to enable improved studies of immunotherapies and combinatorial therapies. This approach will be supported with multimodal in vitro and in vivo modeling as well as clinical material.

The work includes designing and developing new models and validating existing ones.

Your specific duties will include:

• Design of microphysiological systems and organ-on-chips
• Fabrication and validation of microphysiological systems and organ-on-chiInteractions 
• Collaborations with computational scientists and cancer biologists
• Coordination of activities between project partners
• Supervision of research engineer/master's student in the projects

Qualifications

Requirements

• A doctoral degree or an equivalent foreign degree deemed equivalent to a doctoral degree in bioengineering, biotechnology, microtechnology or other relevant fields. This eligibility requirement must be met no later than the time the employment decision is made.
• Research expertise with at least 2 peer-review articles published or in advanced manuscript for

Preferred qualifications

• A doctoral degree or an equivalent foreign degree, obtained within the last three years prior to the application deadline
• Experience in microsystem and microfluidic design and fabrication
• Experience in cancer biology projects
• Teaching and supervision experience
• Excellent ability to collaborate and cooperate with researchers and industry from different disciplines 
• Excellent ability to work independently
• Awareness of diversity and equal opportunity issues, with a specific focus on gender equality
• Excellent communication skills

Great emphasis will be placed on personal skills.

Join us at KTH

KTH shapes the future through education, research and innovation. As a leading international technical university, we play an active role in advancing the transition towards a sustainable society. At KTH, you have the opportunity to grow and develop in a creative and dynamic environment, with good working conditions and attractive benefits. Equality, diversity and equal opportunities are essential to quality and form an integral part of KTH’s core values as a university and public authority.

Learn more about our benefits and what it's like to work and grow at KTH.

Trade union representatives

Contact information to trade union representatives.

To apply for the position

Log into KTH's recruitment system to apply for this position. You are responsible for ensuring that your application is complete according to the instructions in the ad.

The application must include:

• CV including relevant professional experience and knowledge.
• Copy of diplomas and grades from your previous university studies. Translations into English or Swedish if the original documents have not been issued in any of these languages.
• Brief motivation why you want to conduct research, your academic interests and how they relate to your previous studies and future goals. Maximally two pages long.

Your complete application must be received at KTH no later than the last day of application, midnight CET/CEST (Central European Time/Central European Summer Time).

About the employment

The position offered is for, at the most, two years.

A position as a postdoctoral fellow is a time-limited qualified appointment focusing mainly on research, intended as a first career step after a dissertation.

Other information

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It may be the case that a position at KTH is classified as a security-sensitive role in accordance with the Protective Security Act (2018:585). If this applies to the specific position, a security clearance will be conducted for the applicant in accordance with the same law with the applicant's consent. In such cases, a prerequisite for employment is that the applicant is approved following the security clearance.

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Disclaimer: In case of discrepancy between the Swedish original and the English translation of the job announcement, the Swedish version takes precedence.