Division of Drug Discovery and Development
The division of Drug Discovery and Development comprises the two groups Human Antibody Therapeutics and Protein Expression and Characterization.
Human Antibody Therapeutics
The Human Antibody Therapeutics facility supports the development of therapeutic antibodies. We will assist by isolating human antibodies from in-house constructed phage libraries to targets as suggested by the partner PI. It will be of critical importance that the partner PI has a substantial know-how of the biological system/target molecule, either from a clinical or basic scientific aspect. The objective is to deliver a reasonable number of candidate clones for further in vivo characterization and proof-of-concept studies in collaboration with the partner PI.
Protein Expression and Characterization
The Protein Expression and Characterization facility provides recombinant target proteins needed for biochemical screening, biophysical characterization, structural analysis and as well as antigens and antibodies using bacterial and mammalian expression systems. The facility has in-house competence and equipment to characterize purified proteins in detail, like stability and interaction analysis.