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Literature

Study questions

We have written down a set of study questions.

List of Papers

Note: This is a preliminary list of articles that is subject to change 

L2

Mandatory: Mihai Pop: Genome assembly reborn: recent computational challenges.

Paper for student presentation: Vezzi et al on the Feature Response Curve.

Paper for student presentation: Bradnam et al: Assemblathon 2: evaluating de novo methods of genome assembly in three vertebrate species

L3

Storey&Tibshirani

L5

Mandatory: Trapnell and Salzberg: How to map billions of short reads onto genomes

Paper for student presentation: Langmead and Salzberg: Fast gapped-read alignment with Bowtie 2

L6

Mandatory: RNA-seq analysis methods: Garber et al, Nature Methods 8:469-477 (2011)

Optional: Lecture notes on RNA-seq from BB2440 Bioinformatics and biostatistics (fall 2015) (use this to refresh your RNA-seq acquaintance)

Paper for student presentation, STAR: Dobin et al. Bioinformatics 29:15-21 (2013)

Paper for student presentation, DEseq: Anders and Huber. Genome Biol 11:r106 (2010)

L7

Mandatory: ChIP-seq introduction: Furey, Nat Rev Genet 13:840-852 (2012)

Paper for student presentation, MACS: Zhang et al Genome Biol 9:r137 (2008)

L8

Introduction MS-based proteomics: Steen and MannNat Rev Mol Cell Biol. 5:699-711 (2004) [Do not try to read the printable pdf, use the html or readcube versions]

Computational MS-based Proteomics: Noble and Maccoss, PLoS Comput Biol 8(1): e1002296 (2012) 

L9

Assigning SignificanceKäll et al. J Proteome Res, 7 (01):29–34 (2008)

A draft map of the human proteome: Kim et al. Nature 509:575–581 (2014)

L10

Targeted Proteomics: Picotti et al. Cell. 2009 Aug 21;138(4):795-806.

L11

Project Organization: Noble PLoS Comput Biol 5(7): e1000424 (2009)