Precision Nanomedicine Engineering for Personalised Medicine
The research group uses a multidisciplinary approach that combines biology, physics and chemistry to advance our understanding of nanoscale structure and dynamics in biological processes. The aim is to use this information to accelerate the development of the next generation of engineered nanomedicines.
Precision Nanomedicine Engineering for Personalised Medicine, led by Associate Professor Hanna Barriga, has three key focus areas: (A) nanoscale engineering (B) improved disease understanding and (C) performance validation. By combining large datasets with single particle analysis, they use this information to improve our understanding of how disease impacts the performance of nanomedicines to attempt to engineer improved delivery technologies on the nanoscale.
An important part of this research is utilisation of large scale research infrastructure including X rays, neutrons and Cryo EM. This enables characterisation of nanoscale structures which is key to providing mechanistic explanations and enabling the reserachers to map the relationship between nanoscale structure and performance.
The group's long term goal is to use these multidisciplinary datasets to enable the rational design of nanomedicines for specific diseases and patients.
Group leader
