Animal Neurotrauma Modelling
Virtual-Rat: Virtual Analysis of Rat Experiments for Traumatic Brain Injury
Preclinical rat experiments of traumatic brain injury are widely used for neurotrauma research and therapeutic development. Today, the causal pathway from experimental insults, to localized tissue strains, and ultimately the injury onset is unknown. Yet little biomechanical reference exists for researchers to design and improve animal tests. These limitations hinder the development of optimal experiments and incur cruel animal suffering and killing. The Virtual-Rat project aims to develop a high-biofidelity, high-resolution computational rat model with dual applications: i) advance the mechanistic understanding of brain injury by linking computational biomechanics with experimental pathology, and ii) enhance rat experiments by correlating external impact parameters to internal biomechanical responses via an open-access dataset. The implementation of the project is uniquely poised through close collaboration among competent biomechanists, computational engineers, and experimentalists from the Royal Institute of Technology, Chalmers University of Technology (Prof. Johan Davisson), and Karolinska Institutet (Prof. Eric Thelin).
Open position
I am currently looking for a Postdoc working on rat neurotrauma modeling. Please email me with the subject "Postdoc-Name" and attach the following information: your CV, representative publications, and motivation letter.
Contact person: Zhou Zhou; Svein Kleiven
Funded by:
