Peter Nilsson
Professor
Details
Researcher
About me
Affiliation:
- Div of Affinity Proteomics
- Dept of Protein Science, CBH
- SciLifeLab
- KTH Royal Institute of Technology
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- 1998 PhD in Biotechnology, KTH
- 2011 Professor in Proteomics, KTH
- Head of Division of Affinity Proteomics
- Platform Scientific Director in the SciLifeLab Clinical Proteomics and Immunology platform representing the Autoimmunity and Serology profiling unit
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Neuroproteomics, Autoimmunity profiling, Infectious diseases & Multi-disease serology
The research in the group is devoted to highly multiplex protein and antibody profiling in body fluids based on various aspects of affinity proteomics. This is mainly enabled through the development and utilization of different types of protein array formats using proteins and antibodies from the Human Protein Atlas.
The main focus within neuroproteomics is on multiplex protein and autoantibody profiling in plasma, serum and CSF within amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), Alzheimer’s disease, Parkinson’s diseases and psychiatric disorders. (PI Anna Månberg)
The autoimmunity disorders mainly being explored and characterized for their autoantibody repertoires are currently vasculitis, systemic sclerosis, myositis, sarcoidosis and fibrosis. (PI Elisa Pin)
During the early phase of the pandemic, we rapidly developed a highly specific and sensitive high-throughput multiplex bead-based serological assay for SARS-CoV-2 that has been used to analyse over 250,000 samples. We are now extending the assay to provide a platform for multi-disease serology including a wide range of antigens representing various respiratory and infectious diseases.
Combinations of highly multiplex protein, autoantibody and serology profiling in association to studies of infectious diseases and vaccinations are now being emphasized within several international collaborations, with a focus on mosquito spread diseases, currently mainly affecting tropical and subtropical areas, such as dengue, zika and chikungunya, and also malaria.
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Group members
Anna Månberg, researcher
August Jernbom Falk, researcher
Ceke Hellström, research engineer
Charlotta Preger, postdoc
Edvin Ljungquist, research engineer
Elisa Pin, researcher
Eni Andersson, research engineer
Inci Aksoylo, postdoc
Jennie Olofsson, research engineer
Lovisa Skoglund, research engineer
Maria Aspenberg, research engineer
Priscilla Silva, postdoc
Ronald Sjöberg, head of unit
Sára Mravinacová, researcher
Sofia Bergström, researcher
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Alumni at Div Affinity Proteomics