Master's projects, internships, and diploma projects are always available - contact me directly for more information!
Area of research
Sustainable aquaculture and agriculture associated with food security and disease control- microbial and plant biotechnology, mass spectrometry-based proteomics, drug discovery, protein engineering, microbiology, biochemistry, enzymology, genomics, metabolomics.
I am a multidisciplinary scientist with many years of experience in the field of plant and microbial biotechnology and analytical chemistry. My research is focused on sustainable aquaculture and agriculture associated with food security and disease control. Within this, we are mainly working on fungal-like eukaryotic microorganisms (e.g. Saprolegnia parasitica, Phytophthora spp.) which belong to the family oomycetes (water molds) and pathogenic to many plants and animal species. In the lack of effective and environmentally safe treatment, these microorganisms cause major environmental damage and financial loss in agriculture and aquaculture. We are using many bioinformatics, molecular biology, and biochemical approaches to understand the molecular and physiological pathways associated with the development, pathogenicity, and host specificity of pathogens. We also perform large-scale multi-omics (e.g. transcriptomics, proteomics) studies that can also help to identify candidate proteins as potential targets in these microorganisms for disease control.
Another area of my research is focused on modifying the natural composition of plant cell walls by engineering carbohydrate biosynthetic pathways for a wide range of applications using poplar (Populus) and Arabidopsis as experimental model systems. The key aim is not only to understand the molecular function of some of the target genes whose catalytic activity is currently unknown but also to use plant biomass (modified cell wall) in useful industrial applications.
I teach in master’s-and Ph.D.- level courses related to plant and microbial biotechnology. The main topics I cover are related to various applications of metabolic engineering in plants and other microbial organisms. I am also involved in other courses focusing on technical aspects of mass spectrometry-based qualitative and quantitative proteomics.
- Our recent work on COVID-19 highlighted on KTH NEWS. https://www.kth.se/en/aktuellt/nyheter/study-identifies-new-potential-treatments-for-sars-cov-2-1.1034413
- Our project SUSTAIN, which is about disease control in aquaculture, won the KTH Innovation Challenge Tech for the Global Goals 2018. https://www.kth.se/en/innovation/nyheter/and-the-winner-is-1.823885
My research is currently supported by the H2020 FetOpen project NOPEST (http://www.h2020nopest.org/), the Swedish Research Council Formas (https://formas.se/), and the Carls Trygger Foundation (https://carltryggersstiftelse.se).
Co-supervision of PhD students:
Erik Malm, KTH Division of Glycoscience. (Main supervisor Prof Vincent Bulone) Graduated 2014.
Vallentina Gallo, University of Pharma, Italy. (Main supervisor Prof Nelson Marmiroli) Graduated 2018.
Felicia Leijon, KTH Division of Glycoscience. (Main supervisor Prof Vincent Bulone) Graduated 2019.