Cecilia Williams

Professor of Experimental Oncology

Science for Life Laboratory Stockholm
School of Biotechnology
KTH – Royal Institute of Technology
Science for Life Laboratory
Tomtebodavägen 23
Box 1031, SE-171 21 Solna, Sweden
Email: cwil@kth.se


Visiting Professor
Department of Biosciences and Nutrition
Karolinska Institutet
Email: cecilia.williams@ki.se


Adjunct faculty
Department of Biology and Biochemistry
University of Houston
3605 Cullen Blvd., Office #3024
Houston, TX 77204-5056
Email: ceciliawilliams@uh.edu

Short Biography

After graduating from KTH, in the topic of molecular large-scale biotechnology (2002), and performing postdoctoral research in the field of stem cell transcriptomics (2002-2005), I gained expertise in cancer research from the Karolinska Institutet (2005-2009). From 2009 I held a tenure-track faculty position at University of Houston, US, where I led a research group and taught Molecular Biology, and received tenure in 2015. I returned to KTH as professor in 2015, and became Visiting Professor at Karolinska Institutet in 2016.

My research is centered on the signaling pathways of nuclear receptors, in particular the estrogen receptors, and the impact of microRNA and long non-coding RNAs in breast and colorectal cancer. I combine large-scale molecular approaches with focused mechanistic experiments in vitro and in vivo, in order to experimentally define the mechanism of action and functions of nuclear receptor and non-coding RNAs in cancer. My goal is to decipher novel cancer mechanisms and design biomarkers and therapies that can help the development of better therapeutic approaches for the prevention and treatment of cancer. This research is funded by NIH, VINNOVA/EU (Vinnmer fellow), Cancerfonden, and the Stockholm City Council.

Education:

1994   M.Sc. (Civ Ing)  Chemical Engineering/Biotechnology   KTH
2002   PhD (Tekn Dr)   Biotechnology   KTH

Appointments:

Professor, Dept. of Proteomics and Nanobiotechnology, School of Biotechnology, KTH,
2015-present

Visiting Professor, Dept. of Biosciences and Medical Nutrition, Karolinska Institutet,
2016-present

Adjunct Associate Professor, Dept. of Biology and Biochemistry, University of Houston,
2015-present

Associate Professor (tenure), Dept. of Biology and Biochemistry, University of Houston, 2015

Assistant Professor (tenure-track), Dept. of Biology and Biochemistry, University of Houston, 2009-2015

Senior Scientist, Dept. of Biosciences and Nutrition, Karolinska Institutet, 2005-2009

Postdoc/Researcher, Dept. of Gene Technology, School of Biotechnology, KTH 2002-2004

Awards

Excellence in research - Distinguished Faculty Scholar Award – Pre-Tenure (2014).
University of Houston

Teaching:

Molecular Biology, undergraduate course, University of Houston (2010-2012)
Molecular Genetics, graduate course, University of Houston (2010-2015)
Current trends in Proteomics, journal club SciLifelab (2015-)

Dissertations from the group:

2011   Karin Edvardsson: Exploring the genome-wide impact of estrogen receptor alpha and beta in cancer cells. (Karolinska Institutet)                                      

2012   Eylem Aydogdu: Impact of microRNAs in mammary stem cell differentiation and breast cancer. (University of Houston)

2013   Anne Katchy: Exploring estrogen receptor gene regulatory mechanism in breast cancer. (University of Houston)

2014   Philip Jonsson: Transcriptional control of oncogenic processes in breast cancer cells by the estrogen receptors. (University of Houston)

2015 Jun Wang: The Mechanisms of Tumor-suppressive microRNAs in Mammary Stem Cell Development and Triple-negative Breast Cancer (University of Houston)

2015 Trang Nuygen-Vu: Defining Anti-tumorigenic and Anti-inflammatory Effects Mediated by Estrogen Receptor Beta in Colon Epithelial Cells (University of Houston)

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